Department/Affiliation: Biology, Biochemistry & Molecular BiologyPhone: 330-263-2026Office Address: 303B MateerEmail: email@example.com
I continue my molecular investigations of Phytophthora infestans, the plant pathogen responsible for the Irish Potato Famine. In recent years my students and I have established an accessible system using brewer’s yeast, Saccharomyces cerevisiae, to investigate the function of Phytopthora proteins during the infection process. This past year, summer research and I.S. students were able to express nearly 50 pathogen proteins in yeast for phenotypic analysis. Using a growth assay we identified several pathogen proteins that inhibit cell growth. We are now using gene microarrays, to examine the expression level of yeast genes to determine the target of each pathogen protein. In addition, we have been developing assays that allow us to detect pathogen proteins that target common eukaryotic pathways, including the MAPK signaling and the programmed cell death pathways.
Areas of Study
John Gaston Mateer Hall931 College MallWooster, OH 44691Phone: 330-263-2379Fax: firstname.lastname@example.orgHours: M-Th: 8am-11pm, F: 8am-5pm, Sa: 1pm-6pm, Su: 1pm-11pm
1189 Beall Avenue, Wooster, Ohio 44691. (330) 263-2000
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