Annastassia Gallo

Investigating how dopaminergic cells handle a disruption to metal ion homeostasis and identify how such a disruption can lead to metal-dependent dysfunction and disease.

Another enzyme of interest in the same pathway is iron-dependent tyrosine hydroxylase (TH). The Gallo Lab is working on expressing this enzyme in an established bacterial system to study how an imbalance of iron and other metals impacts activity

• Chemistry 111: General Chemistry I
• Chemistry 211: Organic Chemistry Lab I
• Chemistry 240: Inorganic Chemistry
• Chemistry 401: Introduction to Independent Study
• Chemistry 39903: Bioinorganic Chemistry

• Zoë Semersky ’23 (Biochemistry & Molecular Biology), Toward a Comprehensive Framework forInvestigating Copper Dyshomeostasis: The Role of His-Tag Modularity and Alternative Expression Systems in Evaluating Dopamine β-Hydroxylas

• N. Reznik, A. D. Gallo, K. W. Rush, G. Javitt, Y. Fridmann-Sirkis, T. Ilani, N.A. Nairner, S. Fishilevich, D. Gokhman, K. N. Chacón, K. J. Franz, D. Fass. “Intestinal mucin is a chaperone ofmultivalent copper” Cell, 2022, 185 (22), 4206-4215.

• Z. L. Semersky*, A. D. Gallo. “Recent insights into how metal ion dyshomeostasis disrupts dopamine beta-hydroxylase activity”. National American Chemical Society Meeting, Indianapolis, IN, March 26, 2023.
• A. D. Gallo. “From student to professor: Lessons in bioinorganic chemistry and beyond” Kenyon College, Gambier, OH, October 11, 2022.

• Reviewer for Dalton Transactions.
• Duke University (Guest Lecturer)
  General Chemistry II Spring 2020, Spring 20

• American Chemical Society
• ACS Inorganic Chemistry Division
• International Society of Non-Binary Scientists

• Phi Kappa Phi Honor Society
• Phi Beta Delta Honor Society