Annastassia Gallo

Investigating how dopaminergic cells handle a disruption to metal ion homeostasis and identify how such a disruption can lead to metal-dependent dysfunction and disease.

Another enzyme of interest in the same pathway is iron-dependent tyrosine hydroxylase (TH). The Gallo Lab is working on expressing this enzyme in an established bacterial system to study how an imbalance of iron and other metals impacts activity

• Chemistry 111: General Chemistry I
• Chemistry 211: Organic Chemistry Lab I
• Chemistry 240: Inorganic Chemistry
• Chemistry 401: Introduction to Independent Study
• Chemistry 39903: Bioinorganic Chemistry
• CHEM 39904 Advanced Inorganic Chemistry

• Eli Harvey | Chemistry ’24 | Fall 2023 – Spring 2024“Interrogation of the Dopamine Beta-Hydroxylase Mechanism through Biomimetic Modeling”
   Current: Graduate student at the University of Pennsylvania

• Seth Owens | BCMB ’24 | Fall 2023 – Spring 2024 “The Effect of Titanium on Catecholamine Enzyme Tyrosine Hydroxylase”
  Current: Applying to Physical Therapy graduate programs

• Mary Payne | BCMB ’24 | Fall 2023 – Spring 2024 “Toward Understanding how metal dyshomeostasis impacts dopamine betahydroxylase activity”
  Current: Quality Lab Technician at AkzoNobel, Columbus, OH
• Mary Sirois | Chemistry ’24 | Fall 2023 – Spring 2024 “Soak Up the Sun: Exploring the Ability of Quantum Dots to Increase PAR Transmission in Seaman Corporation’s Dura-Grow Greenhouse Film to Improve Plant Growth”
  Current: Graduate student at Penn State
• Sam L. Belsky | BCMB ’23 | Spring 2023  “Interrogation of a Conserved Overlap Between Cofactor and Substrate Binding Domains to Facilitate Crosstalk-Induced Conformational Changes in Class A Flavin Monooxygenases: A Case Study of 6-Hydroxynicotinate-3-Monooxygenase” Current: Graduate student at University of Illinois – Urbana Champaign

• Zoë L. Semersky | BCMB ’23 | Fall 2022 – Spring 2023 “Toward a Comprehensive Framework for Investigating Copper Dyshomesotasis: The Role of His-Tag Modularity and Alternative Expression Systems in Evaluating Dopamine 𝛽– Hydroxylase”
  Current: Graduate student at University of Wisconsin – Madison, Integrated Program in
  Biochemistry
  

• A. D. Gallo, K. J. Franz. Grab ‘n Go: Siderophore-Binding Proteins Provide Pathogens a Quick Fix to Satisfy their Hunger for Iron. ACS Central Science, 2020, 6, 456-458.
  
• A. D. Gallo, M. R. Zierden, K. E. Jones, L. A. Profitt, C. P. Bonafide, A. M. Valentine. TiO2 exposure alters transition metal ion quota in Rhodococcus ruber GIN-1. Metallomics, 2020, 12, 8-11.

• Z. L. Semersky*, A. D. Gallo. “Recent insights into how metal ion dyshomeostasis disrupts dopamine beta-hydroxylase activity”. National American Chemical Society Meeting, Indianapolis, IN, March 26, 2023.
• A. D. Gallo. “From student to professor: Lessons in bioinorganic chemistry and beyond” Kenyon College, Gambier, OH, October 11, 2022.

• Reviewer for Dalton Transactions.
• Duke University (Guest Lecturer)
  General Chemistry II Spring 2020, Spring 20

• American Chemical Society
• ACS Inorganic Chemistry Division
• International Society of Non-Binary Scientists

• Phi Kappa Phi Honor Society
• Phi Beta Delta Honor Society